CD235a-PE, 11E4B-7-6, 100 Tests, CE

A07792


The CD235a antigen, also called Glycophorin A, is a transmembrane, single-pass glycoprotein that contains carbohydrate, mostly in the form of sialic acid. CD235a has a molecular weight of 10 kDa. It is expressed by erythroid precursors and erythrocytes. Glycophorins A carries the antigen determinants for the MNS blood groups and has been proposed to be an inhibitor of hemagglutination and hemolysis. Glycophorin A binds siglec 5, and may also serves as receptor for cytokines and pathogens, including the malaria parasite, Plasmodium falciparum and some viruses, including influenza virus and hepatitis A virus.

Especificaciones

Target Species Human
Specificity CD235a
Other Names CD235a, Glycophorin A
Fluorochrome PE
Regulatory Status CE
Size 100 Tests
Format Liquid
Flow Product Line IOTest
Clone 11E4B-7-6 (KC16)
Isotype IgG1 Mouse
Clone Description The 11E4B-7-6 (KC16) antibody binds to the amino acid sequence 27-39 of glycophorin A and has no reactivity to glycophorin B. It reacts with immature erythrocytes including erythroblasts, proerythroblasts and reticulocytes.

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IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
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